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Dr. Zhong-Cheng Luo

Research Institute
Mount Sinai Hospital
Joseph and Wolf Lebovic Health Complex
600 University Avenue
Toronto, Ontario
M5G 1X5

Tel.: 416-586-4800 ext.2421

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Dr. Zhong-Cheng Luo


Dr. Zhong-Cheng Luo is an Associate Scientist in Perinatal and Paediatric Epidemiology, a research area in pregnant women and their infants to understand the causes and consequences of adverse pregnancy/birth outcomes and infant health.

He has been conducting birth cohort studies on gestational diabetes and adverse fetal growth (poor or excessive) to understand their causes, etiologic mechanisms, prognostic biomarkers and the impacts on postnatal metabolic health in the offspring. He has been working with Indigenous community partners in studies on disparities in maternal and infant health in Indigenous vs. non-Indigenous populations, and interventions to improve Indigenous maternal and infant health.

Dr Luo’s transdisciplinary birth cohort studies on perinatal determinants of infant metabolic health have contributed to a better understanding of the impacts of glucose tolerance during pregnancy and early postnatal growth pattern on insulin sensitivity and beta-cell function in infants, and the roles of adipokines, polyunsaturated fatty acids and oxidative stress.

Dr Luo’s studies on Indigenous perinatal and infant health have contributed to a better knowledge on the disparities in birth outcomes, infant mortality and morbidities in First Nations and Inuit vs. non-Indigenous populations in Canada.

Dr Luo has developed international collaborations with the Shanghai Birth Cohort, and the Sino-Canadian Healthy Life Trajectories Initiative - A Multifaceted Community-Family-Mother-Child Intervention Study for the Prevention of Childhood Obesity in China.

At a Glance

Dr. Luo employs a birth cohort approach to study perinatal determinants and biomarkers of gestational diabetes, adverse fetal growth and postnatal metabolic health in infants.

Dr. Luo works with Indigenous partners in studies towards better knowledge for improving Indigenous maternal and infant health.

Major Research Activities

Dr. Luo’s recent research focuses on gestational diabetes, adverse fetal growth, developmental origins of metabolic health, and Indigenous maternal and infant health. He is the Principal Investigator (PI) on two ongoing projects funded by the Canadian Institutes of Health Research (CIHR): 1) Understanding early life origins of sex difference in insulin sensitivity; 2) Towards a better understanding of high infant hospitalization rates in First Nations and Inuit.

He is also a co-PI in a large Canadian birth cohort, the 3D (Design, Develop, Discover) cohort developed by the Integrated Research Network in Perinatology of Quebec and Eastern Ontario, and is the lead in the fetal growth study of the 3D cohort on perinatal determinants of infant metabolic and neuro-developmental health.