/ opportunities / archive / principal-investigators-in-cellular-systems-and-developmental-biology-104159-(2022-06-30)

Sinai Health: Lunenfeld-Tanenbaum Research Institute

Principal Investigators in Cellular, Systems and Developmental Biology        


Toronto, ON, Canada
Open Date
March 18, 2022
June 30, 2022 at 11:59 PM Eastern Time




Application Link

Interfolio Faculty Search: 


The Lunenfeld-Tanenbaum Research Institute of Sinai Health, a University of Toronto affiliated biomedical research centre, is recruiting emerging leaders in the area of Cellular and Developmental Biology. The appointments will be for Principal Investigators (rank equivalent to Assistant Professor).

We seek applicants who will develop innovative, outstanding and independent programs in Cellular and Developmental Biology.  Research approaches include, but are not limited to, the application of functional genomics, proteomics, metabolomics, epigenomics, single-cell analytics, and tissue engineering to investigate complex systems from the molecular to organism level including humans and/or model animal systems. Topic areas encompass reproductive, developmental, and regenerative biology, cellular physiology, and network biology.

The successful candidates will join the Lunenfeld-Tanenbaum Research Institute’s faculty who are internationally renowned for their work in signalling networks, cancer and developmental biology, structural biology, imaging, high throughput screening and proteomics. With numerous discoveries in basic and applied research in cancer, developmental biology, stem cell biology, diabetes, genetic disorders and women’s and infants’ health, the Lunenfeld-Tanenbaum Research Institute is committed to excellence in health research and the training of young investigators. The Institute provides a research-intensive environment with modern and innovative core facilities that include proteomics, next-generation sequencing, single cell platforms, robotics and imaging that drive technology development and are housed in the Network Biology Collaborative Centre. Sinai Health is also the home of The Centre for Phenogenomics, a state-of-the-art national facility for mouse models.

Lunenfeld-Tanenbaum Research Institute labs engage in productive collaborations within the Institute, Sinai Health, the larger University of Toronto community, and beyond. The University of Toronto has one of the most concentrated biomedical research communities in the world, including 9 academic hospital research institutes that are fully affiliated with the University. Toronto is a vibrant, safe and multicultural city with excellent quality of life.


Investigators at the Lunenfeld-Tanenbaum Research Institute are appointed to independent positions equivalent to Assistant, Associate or Full Professor, depending on experience; preference for this opportunity will be given to individuals qualifying at the level of Assistant Professor. Investigators will be cross-appointed to appropriate research or clinical department(s) at the University of Toronto.

Successful candidates will hold a PhD and/or MD degree, with postdoctoral experience and an established record of research accomplishment as demonstrated by outstanding publications, presentations at international conferences, awards and accolades, as well as strong endorsement by referees of high international standing. The successful candidates will be expected to initiate and lead innovative, independent, and externally funded, research program of the highest international calibre.

We offer competitive and generous salary and start-up packages commensurate with experience and qualifications (illustrative salary range between $140,000 and $160,000).

The Lunenfeld-Tanenbaum Research Institute and Sinai Health are strongly committed to diversity within its community and especially welcome applications from racialized persons / persons of colour, women, Indigenous / Aboriginal People of North America, persons with disabilities, and members of sexual minority groups, and others who may contribute to the further diversification of ideas.

The Lunenfeld-Tanenbaum Research Institute and Sinai Health recognize that scholars have varying career paths and that career interruptions due to personal circumstances can be part of an excellent academic record. Candidates are encouraged to explain any personal circumstances in order to allow for a fair assessment of their application. Search committee members have been instructed to give careful consideration to, and be sensitive to the impact of, career interruptions in their assessments.

As part of the University of Toronto and Sinai Heath implementation of its Canada Research Chairs Equity, Diversity & Inclusion Action Plan, the successful candidate in this search MAY BE eligible for nomination for a CRC Tier 1 or CRC Tier 2 Chair if they self-identify as a member of the following federally designated groups, as defined by the Employment Equity Act (women, visible minorities, persons with disabilities, and Indigenous Peoples), or as trans, non-binary, or Two-Spirit. The nominee’s research area must align with the subject matter eligibility of CIHR.

Tier 2 Chairs are intended for exceptional emerging scholars. Nominees should be within ten years of receiving their PhD or MD degree.  Applicants who are more than 10 years from having earned their highest degree (and where career breaks exist, such as maternity, parental or extended sick leave, clinical training, etc.) may have their eligibility for a Tier 2 chair assessed through the program’s Tier 2 justification process.

For further Information on the federally endowed Canada research Chairs program, open to all nationalities, including eligible criteria, please consult the Canada Research Chairs website.  



Applications should include:

  1. A one-page structured summary that includes: A) a brief education/training history; B) a summary of the applicant’s most important research contributions (up to five), and C) an abstract of the research plan
  2. A cover letter
  3. A research statement highlighting the proposed research program (not exceeding 3 pages, including figures)
  4. A complete curriculum vitae
  5. Three reference letters

Applications should be submitted via the Interfolio website prior to June 30th, 2022. The search will remain open until a suitable candidate is identified. The earliest start date is October 1st, 2022, or a date to be mutually agreed upon.

Applicants needing additional information can contact Dr. Stephen Lye at PI_search@lunenfeld.ca. E-mailed applications will not be accepted.


As part of your application, you will be asked to complete a brief Diversity Survey directly on the Interfolio site. This form is voluntary and any information directly related to you is confidential and cannot be accessed by the search committee. Results will be aggregated for institutional planning purposes as part of Sinai Health’s Equity, Diversity and Inclusion initiative.


In accordance with Institute’s policy and legislated health and safety requirements, employment is conditional upon the verification of credentials, completion of a health review, and demonstrating proof of immunity and vaccination status of vaccine-preventable diseases.

Sinai Health is a scent sensitive environment, and all members of the community are expected to refrain from wearing or using scented products while visiting or working at the Institute. We also support a barrier-free workplace supported by the Institute’s accessibility plan, accommodation and disability management policies and procedures. Should you require accommodation at any point during the recruitment process, including accessible job postings, please contact the Lunenfeld-Tanenbaum Human Resources Department. All qualified applicants are strongly encouraged to apply; however, in accordance with Canadian immigration requirements, Canadians and permanent residents will be given priority.